A new paper from one of AlmaScience Researchers, Bruno Viegas, has been published and we couldn't be more proud to share it.
“Digital microfluidics (DMF) is an exciting technology for liquid handling, enabling low-volume droplet motion in electrode arrays, commonly mediated by voltage signals. Such technology allows for interesting applications in the field of molecular diagnostics, namely isothermal nucleic acid amplification for the detection of biomarkers in low-volume samples. We developed a digital microfluidics platform capable of performing loop-mediated isothermal amplification (LAMP) of DNA while fitting under a fluorescence microscope, thus enabling distinction between amplifying and non-amplifying samples, as well as real-time monitoring the reaction progression. This technology was used for the detection and quantification of c-Myc, a cancer biomarker involved in cell growth, proliferation and metabolism, which cumulatively intervenes in tumorigenesis.” – says the author.
Congratulations to Bruno and all researchers involved.
DOI: https://doi.org/10.3390/bios12040201 (registering DOI)